Aurora's Guide To Mouse Colony Management

Questions 5 Publications 81 Questions related to Mouse Colony Management. JAXConnect Colony Management is an intuitive and powerful online project management tool that saves you time without sacrificing control.

Perilipin 2 Promotes Obesity And Progressive Fatty Liver Disease In Mice Through Mechanistically Distinct Hepatocyte And Extra Hepatocyte Actions Orlicky 2019 The Journal Of Physiology Wiley Online Library

Mouse Breeding Colony Management 1.

Aurora's guide to mouse colony management. Mating pair- one male one female. Genotyping report and example. However the reproductive life span of mice is significantly shorter at 7-8 months.

Colony Management Considerations Many labs and companies have already chosen to breed and maintain their own colonies of ALS mouse models rather than obtain these commercially. Mouse colony management software programs come with different combinations of these features and more. A Guide to the Behavior Enrichment of Laboratory Rodents.

It is the most widely used genetic background for genetically modified mice for use as models of human disease. Auroras Guide to Mouse Colony Management at MIT -Aurora Burds Connor Feb 2007. They are the most widely used and best-selling mouse strain due to the availability of congenic strains easy breeding and robustness.

SoftMouse is the leading brand in online mouse colony management web-based and mobile solutions. We reviewed the 5 the best software solutions for lab animal colony management to help you choose the right option. Genotyping and identification See policy UW-4096 Genotyping of Mice and Rats.

Save by purchasing the access to these 3 recordings for your training program. It was developed by a mouse researcher to satisfy the need for simplicity usability and interactivity. The importance of confirming genotype.

Mouse Colony Management Fundamentals Webinar Recording This presentation covers strategies for selection of animals and breeding schemes expansion of a colony including calculation examples practical tips on mouse. The Introduction to Colony Management MiniCourse Program consists of self-paced MiniCourses that provide an introduction to some important topics related to mouse colony management. Therefore in addition to considering specific questions of preclinical study design using ALS mouse models it is also important to consider the current best practices and information regarding breeding and maintaining.

Refer to the Glossary for definitions of technical terms mentioned below. Genotype cage card template. Its important to determine the number of breeding pairs you need to supply sufficient mice for your experiments.

Common for strains with good fecundityLeave pair together continuously whenever possible to maximize production. General Mouse Information i. This book provides information on managing mouse and rat colonies colony management from a genetics and reproductive standpoint and guidance for troubleshooting colony performance.

Topics covered include confirming archiving and maintaining mouse strains as well as important considerations for breeding strategies. Younger mice generally produce smaller litters and. Why when and how to archive a.

Colony management best practice. They are safe reliable economical efficient and ensure. Most mice reach sexual maturity males and females at 4-7 weeks of age.

Maintaining a breeding colony of mice is one method of generating and then ensuring an available supply of experimental subjects with desired characteristics. 24-hour access to mouse-level colony information gets you the answers you need when you need them. One of the following breeding schemes may be used.

Work from your Home your Lab or Remotely with the SoftMouseNET mouse colony management software and online database for mouse breeding software management in the cloud. Guidebook on Mouse and Rat Colony Management. Genotyping and Identification Procedures SOP.

The most efficient lIMS system to manage your mouse colony data. The colony manager is responsible for pregnancy and birth checks cage card documentation and for separating and weaning according to the guidelines below. The Breeding Colony Size Planning Worksheet pdf is a very useful resource.

If you will be breeding animals and do. The average mouse lives approximately 25 years. Any recurring problems with mouse breeding colony management will be brought to the attention of the IACUC.

If animals will be bred for the purposes of research an application must be submitted and approved by the ARC. Establishing reproductive characteristics and keeping accurate records. Explore the latest questions and answers in Mouse Colony Management and find Mouse Colony Management experts.

35-R-0001 Laboratory Animal Welfare Public Health Service Assurance Number. Recommendations for housing laboratory rodents are based on the 2010 edition of the NIH Guide for the Care and Use of Laboratory Animals the Guide pp. C57BL6 often referred to as C57 black 6 C57 or black 6 is a common inbred strain of laboratory mouse.

Colonies of Laboratory Mice A Jackson Laboratory Resource Manual This manual describes breeding strategies and techniques for maintaining colonies of laboratory mice. MouseJ is a free mouse colony management software designed for laboratories. Return to MiniCourse Catalog.

608 890-1273 USDA Research Registration. This best practice guidance covers critical aspects of breeding colony management and archiving of GA mouse strains including. Due to all these factors the art and science of managing mouse colonies effi ciently is more important than ever.

It defines guidelines necessary to establish the colony and describes screening for germline transmission. The management of mouse colonies created by gene targeting is described in this unit. Although mice breed readily when left to themselves it is helpful to have a working knowledge of.

This review primarily covers software for managing mice and other rodent colonies. BRMS Mouse Breeding Core Colony Management can provide you with reliable economical and efficient breeding colonies of mice to support research projects. Learn from these three experts on how to manage a breeding colony of transgenic mice.

These techniques have been developed and used by The Jackson Laboratory for nearly 80 years. Colony managers oft en consult us for advice and rightly so for our mouse husbandry experts have been using and refi ning mouse colony management techniques for over 75. This document provides a high level introduction to best practice in mouse colony management.

Colony Management Tips 15 Mate early 6-12 weeks Choose breeders carefully o Avoid selection pressure Replace breeders on a rotation monthly o Mixed-age colony breeds more consistently o Requires having young breeders available Replace non-productive breeders ASAP 60-90 days Collect your own breeding statistics o Evaluate regularly. Learn how to size experimental mouse colonies to accurately match your research needs in a consistent manner with a minimum use of resources.

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